Monday, February 03, 2014

What is primary hypertension?

There are two main categories of hypertension: primary hypertension and secondary hypertension. Primary hypertension, also known as essential hypertension, is responsible for 90% to 95% of all hypertension. 

Secondary hypertension accounts for the remaining percentage.

The genesis of primary hypertension is multifactorial and complex. Primary hypertension usually begins insidiously as a benign disease, slowly progressing to malignant state.

A simplistic explanation of the pathogenesis is that there is specific mechanism appear to be involved in the development of primary hypertension: altered regulation of the sympathetic nervous system, abnormalities of the rennin-angiotensin- aldosterone system, salt sensitivity, as well as other vascular and hormonal factors. 

Carefully managed treatment, which may include lifestyle modification and drug therapy, improves the prognosis. Untreated, it carries a high mortality rate.

Risk factors associated with the development of primary hypertension include elevated blood lipid levels, smoking, diabetes, age older than 60 years, gender and family history of cardiovascular disease.

The majority of patients who developed primary hypertension do so between 20 to 50 years of age. 

Primary hypertension has a strong link with obesity and insulin resistance and it is greater in those patients with central obesity.

Obesity and the concomitant resultant hyperinsulinemia stimulate the sympathetic nervous system, thereby contributing to hypertension.
What is primary hypertension?

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