Sunday, May 31, 2015

Resistant hypertension

Hypertension has generally been defined as resistant when it remains uncontrolled despite a ‘good’ regimen of 3-antihypertensive drugs at full dosage.

Resistant hypertension is associated with multiple risk factors and organ damage. The most common reason for resistant hypertension is systolic hypertension in older individuals, in whom a favorable outcome has been linked to the degree of BP lowering, rather than to the drug type employed.

Poor adherence failure to modify lifestyle, inadequate treatment, white-coat hypertension, and secondary hypertension are all common aetiologies.

In patient with resistant hypertension, subclinical organ damage itself may be responsible for high blood pressure values, but it is also the result of detrimental effects of hypertension on large arteries as well as on the microvascular network.

Resistant hypertension is relatively common in hypertension clinics because of selection by referral, and it is seen in 13-20% of such patients.
Resistant hypertension

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